How To Raise Lupus Awareness
Lupus is an autoimmune disease that affects millions of people around the world. Despite its prevalence, many people are unaware of how lupus affects individuals and their families. This is where being aware of lupus comes into play. We can help people understand the signs and symptoms of lupus, promote early detection, reduce the stigma […]
The Mucopolysaccharidoses Disease Series: Type IV
In the last blog update, we discussed on Mucopolysaccharidoses (MPS) Disease series with MPS Type III, also known as Sanfilippo Syndrome. In today’s blog, we continue the series with the next variation of the disease; MPS Type IV. MPS Type IV is also known as Morquio syndrome. This metabolic condition is very rare to happen, […]
The Mucopolysaccharidoses Disease Series: Type III
In the previous blog post, we have discussed on MPS Type II diseases, which gene is getting mutated and how the mutation affects the human body. We also talked about the symptoms for MPS Type II. Now, we will touch on MPS Type III. MPS III also known as Sanfilippo Syndrome causes the body unable […]
The Mucopolysaccharidoses Disease Series: Type II
On the previous blog post, we discussed on what Mucopolysaccharidoses Disease (MPS) is and how genetics play an important role for the disease. We also touched upon Type 1 of the MPS disease, what genes are involved and how the mutation cause changes to the human body. This week, we will talk about MPS Type […]
The Mucopolysaccharidoses Disease Series: Type I
Before we jump dive right in, a lot of you may wonder what is Mucopolysaccharidoses (MPS) Disease? Most if not, all might never even hear of this disease. MPS are a group of disorders that fall under the inherited lysosomal storage disorders (LSD). LSD is caused by the defective function of lysosomes that is due […]
Have You Ever Heard of Metachromatic Leukodystrophy?
Lysosomal storage disorders (LSDs) are inborn metabolic abnormalities characterized by the excessive accumulation of substrates in a variety of organ cells as a result of lysosome dysfunction. They contribute significantly to significant morbidity and mortality by causing malfunction in the organs where they accumulate. Dubbed as one of the most prevalent leukodystrophies in 2020, MLD […]
What is Gaucher Disease?
Gaucher Disease is an inherited metabolic disorder characterized by the buildup of harmful amounts of certain fats (lipids), specifically the glycolipid glucocerebroside, throughout the body, most notably in the bone marrow, spleen, and liver. It’s one of the most common Lysosomal Storage Disease in Malaysia and Singapore with 3 occurrences in every 1 000 000 […]
Lysosomal Storage Disease – What YOU Need To Know
Lysosomes are membrane-enclosed organelles that contain an array of enzymes capable of breaking down proteins, nucleic acids, carbohydrates, and lipids. Lysosomes are enzyme sacs within cells that digest large molecules and recycle the fragments to other parts of the cell. Several critical enzymes are required for this process. If one of these enzymes becomes defective […]